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Experimental Compounds

PT-141 – 10mg

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Size: 10mg
SKU: YPB.274
Category: Experimental Compounds

Research Use Only

This product is sold strictly for in vitro research and laboratory use only, consistent with 21 CFR § 809.10(c)(2)(i). It is not a drug, dietary supplement, food, cosmetic, or medical device. It has not been evaluated or approved by the FDA or any comparable foreign authority for any therapeutic, diagnostic, prophylactic, veterinary, or cosmetic use, and it is not intended for human or animal consumption, application, ingestion, injection, inhalation, or any in vivo use.

Buyer eligibility. By purchasing, you represent that you are at least 21, a qualified researcher or research-affiliated professional, that your purchase is for a lawful in vitro research purpose, and that purchase and possession are lawful in your jurisdiction.

No protocols or guidance. Any product information on this page is provided for bibliographic and laboratory-reference purposes only. PeptaLux does not provide research protocols, dosing guidance, administration instructions, or product recommendations.

Terms of sale. Sold AS IS, AS AVAILABLE, with all warranties disclaimed to the maximum extent permitted by law. Buyer assumes all risk and indemnifies PeptaLux as set out in the Terms and Conditions, Refund Policy, Shipping Policy, and Privacy Policy, which you accept by purchasing.

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Description

Bremelanotide (PT-141) is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH), originally derived from the Melanotan-II scaffold via removal of the C-terminal amide and lactam-bridge cyclization. In vitro and rodent-model research literature has characterized its interaction with the melanocortin-3 and melanocortin-4 receptors (MC3R/MC4R) and downstream cAMP/PKA signaling pathway activation in central nervous system tissue (Molinoff et al., Ann. N.Y. Acad. Sci., 2003). Rodent-model investigations have examined its association with melanocortin-pathway central nervous system signaling cascades and downstream autonomic-axis modulation patterns (Pfaus et al., Proc. Natl. Acad. Sci. USA, 2004). Findings in in vitro / animal studies do not necessarily translate to other systems.

PT-141 (Bremelanotide) is a synthetic melanocortin receptor agonist peptide.

Specifications
Molecular formula
C50H68N14O10
Molecular weight
1025.18 g/mol
Sequence
Ac-Nle-cyclo(D-H-(D-Phe)-R-W-K) (7 residues, modified, lactam-cyclized)
Appearance
White lyophilized powder
Solubility
Soluble in sterile water
Storage
-20°C, protected from light, sealed container
Sources & Citations
Shipping & Returns

Shipping

PeptaLux ships exclusively from US-based fulfillment. US orders only. Standard shipping: 3-5 business days. Priority shipping: 1-2 business days. Free shipping on research orders over $250.

Storage & Handling

Storage requirements vary by compound. See “Storage” under Specifications above for this product’s specifics. Customers are responsible for proper storage on receipt.

Returns

All sales are final. Limited exceptions for confirmed non-delivery and PeptaLux-error situations. See our full Refund Policy for the operative terms. View Refund Policy

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