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Small Molecules (RUO)

SS-31 – 50mg

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Size: 50mg
SKU: YPB.246
Category: Small Molecules (RUO)

Research Use Only

This product is sold strictly for in vitro research and laboratory use only, consistent with 21 CFR § 809.10(c)(2)(i). It is not a drug, dietary supplement, food, cosmetic, or medical device. It has not been evaluated or approved by the FDA or any comparable foreign authority for any therapeutic, diagnostic, prophylactic, veterinary, or cosmetic use, and it is not intended for human or animal consumption, application, ingestion, injection, inhalation, or any in vivo use.

Buyer eligibility. By purchasing, you represent that you are at least 21, a qualified researcher or research-affiliated professional, that your purchase is for a lawful in vitro research purpose, and that purchase and possession are lawful in your jurisdiction.

No protocols or guidance. Any product information on this page is provided for bibliographic and laboratory-reference purposes only. PeptaLux does not provide research protocols, dosing guidance, administration instructions, or product recommendations.

Terms of sale. Sold AS IS, AS AVAILABLE, with all warranties disclaimed to the maximum extent permitted by law. Buyer assumes all risk and indemnifies PeptaLux as set out in the Terms and Conditions, Refund Policy, Shipping Policy, and Privacy Policy, which you accept by purchasing.

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Description

Elamipretide (SS-31) is a synthetic mitochondria-targeted aromatic-cationic tetrapeptide of the Szeto-Schiller class, designed to selectively partition into the inner mitochondrial membrane through electrostatic and hydrophobic interaction with cardiolipin. In vitro and rodent-model research literature has characterized its interaction with cardiolipin in the inner mitochondrial membrane and downstream effects on cytochrome c oxidase activity and electron-transport-chain efficiency (Birk et al., J. Am. Soc. Nephrol., 2013). Rodent-model investigations have examined its association with mitochondrial membrane-potential signaling pathways and reactive oxygen species mitochondrial-flux dynamics (Szeto, AAPS J., 2006). Findings in in vitro / animal studies do not necessarily translate to other systems.

SS-31 (D-Arg-Dmt-Lys-Phe-NH2) is a mitochondria-targeted tetrapeptide. Also known as Elamipretide.

Specifications
Molecular formula
C32H49N9O5
Molecular weight
639.79 g/mol
Sequence
(D-Arg)-(2',6'-dimethyl-Tyr)-K-F-NH2 (4 residues, modified)
Appearance
White lyophilized powder
Solubility
Soluble in sterile water
Storage
-20°C, protected from light, sealed container
Sources & Citations
Shipping & Returns

Shipping

PeptaLux ships exclusively from US-based fulfillment. US orders only. Standard shipping: 3-5 business days. Priority shipping: 1-2 business days. Free shipping on research orders over $250.

Storage & Handling

Storage requirements vary by compound. See “Storage” under Specifications above for this product’s specifics. Customers are responsible for proper storage on receipt.

Returns

All sales are final. Limited exceptions for confirmed non-delivery and PeptaLux-error situations. See our full Refund Policy for the operative terms. View Refund Policy

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